Full-wave nonlinear ultrasound simulation on distributed clusters with applications in high-intensity focused ultrasound

Full-wave nonlinear ultrasound simulation on distributed clusters with applications in high-intensity focused ultrasound

Model-based treatment planning and exposimetry for high-intensity focused ultrasound requires the numerical simulation of nonlinear ultrasound propagation through heterogeneous and absorbing media. This is a computationally demanding problem due to the large distances travelled by the ultrasound waves relative to the wavelength of the highest frequency harmonic. Here, the k-space pseudospectral...

High-Intensity Focused Ultrasound –

High intensity focused ultrasound (HIFU).

INTRODUCTION Curative treatments for localized prostate cancer, from least invasive to most invasive, include brachytherapy, cryosurgery, three-dimensional conformal radiation therapy, external beam radiation therapy, and radical prostatectomy. A patient with localized, low risk or intermediate risk prostate cancer who is diagnosed at an early age and receives one of these treatments has only a...

Nonlinear absorption in biological tissue for high intensity focused ultrasound.

In recent years the propagation of the high intensity focused ultrasound (HIFU) in biological tissue is an interesting area due to its potential applications in non-invasive treatment of disease. The base principle of these applications is the heat effect generated by ultrasound absorption. In order to control therapeutic efficiency, it is important to evaluate the heat generation in biological...

Rapid full-wave phase aberration correction method for transcranial high-intensity focused ultrasound therapies

BACKGROUND Non-invasive high-intensity focused ultrasound (HIFU) can be used to treat a variety of disorders, including those in the brain. However, the differences in acoustic properties between the skull and the surrounding soft tissue cause aberrations in the path of the ultrasonic beam, hindering or preventing treatment. METHODS We present a method for correcting these aberrations that is...